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The correlation between grip strength and plasma NfH levels in SOD1 mice during disease progression.

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posted on 20.02.2013, 02:26 by Ching-Hua Lu, Axel Petzold, Bernadett Kalmar, James Dick, Andrea Malaspina, Linda Greensmith

The graphs show the relationship between mean grip strength (g) and plasma NfH phosphoform levels (ng/mL) in individual SOD1 mice (n = 16) at 65, 90, 105, and 120 days of age. A) There is a strong inverse correlation between plasma NfHSMI34 levels and grip strength in SOD1 mice (Spearman’s rho = −0.583, p<0.0001). The best-fit line (dashed line) is shown. B) There is a moderate inverse correlation between plasma NfHSMI35 and grip strength in SOD1 mice (Spearman’s rho = −0.335, p<0.0001). The best-fit line (dashed line) is shown.

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