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T cell activation modulates HuR binding towards the hIL-3 ARE-rich region.

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posted on 2014-03-21, 04:04 authored by José A. González-Feliciano, Marimar Hernández-Pérez, Luis A. Estrella, Daisy D. Colón-López, Armando López, Marina Martínez, Kirla R. Maurás-Rivera, Clarivel Lasalde, Daviana Martínez, Félix Araujo-Pérez, Carlos I. González

(A) HuR EMSA supershift analysis was carried out with Jurkat cytoplasmic extracts activated at 0, 6, 12 and 24 hours. (B) Graphic representation of HuR supershift quantification during T cell activation. Values represent mean ± standard error of the mean (SEM) from two experiments. Fold changes were normalized to 0 hours of T cell-activation with PMA/Ionomycin.