Figure_6.tif (565.41 kB)
T cell activation modulates HuR binding towards the hIL-3 ARE-rich region.
figure
posted on 2014-03-21, 04:04 authored by José A. González-Feliciano, Marimar Hernández-Pérez, Luis A. Estrella, Daisy D. Colón-López, Armando López, Marina Martínez, Kirla R. Maurás-Rivera, Clarivel Lasalde, Daviana Martínez, Félix Araujo-Pérez, Carlos I. González(A) HuR EMSA supershift analysis was carried out with Jurkat cytoplasmic extracts activated at 0, 6, 12 and 24 hours. (B) Graphic representation of HuR supershift quantification during T cell activation. Values represent mean ± standard error of the mean (SEM) from two experiments. Fold changes were normalized to 0 hours of T cell-activation with PMA/Ionomycin.
