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TNF-α attenuates Tgf-β2 expression in LRP1 expressing macrophages.

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posted on 20.02.2013, 11:03 by Selen Catania Muratoglu, Shani Belgrave, Anna P. Lillis, Mary Migliorini, Susan Robinson, Elizabeth Smith, Li Zhang, Dudley K. Strickland

a) Bone marrow derived macrophages were treated with TNF-α overnight. Total mRNA from each sample was isolated and analyzed by qRT-PCR array analysis using the atherosclerosis array from SABiosciences™. The levels of Tgf-β2 (a) and SerpinB2 (b) are shown for LRP1+/+ and macLRP1-/- cells (n = 3 for each cell type; *p = 0.007, Students t-test).

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