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TKIs and SB525334 synergistically inhibit proliferation of UMSCC25 cells.

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posted on 06.05.2015 by Emily K. Kleczko, Jihye Kim, Stephen B. Keysar, Lydia R. Heasley, Justin R. Eagles, Matthew Simon, Marianne E. Marshall, Katherine R. Singleton, Antonio Jimeno, Aik-Choon Tan, Lynn E. Heasley

A CyQUANT Direct Cell Proliferation Assay was performed on UMSCC25 cells treated with a concentration range of gefitinib and SB525334, alone and in combination. The experiment was performed in the absence (A.) or presence (B.) of 0.3μM AZD4547. The combinatorial indices (CI) were calculated with CalcuSyn Software and are presented in the tables below each graph.

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