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Download fileTIMP-1-GPI promotes wound healing in vitro.
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posted on 2012-04-27, 01:36 authored by Roghieh Djafarzadeh, Matthias Sauter, Susan Notohamiprodjo, Elfriede Noessner, Pankaj Goyal, Wolfgang Siess, Markus Wörnle, Andrea Ribeiro, Susanne Himmelein, Thomas Sitter, Peter J. NelsonA monolayer of human primary mesothelial cells was cultured with an experimental wound model insert provided by Ibidi GmbH (Munich, Germany). Removal of the insert yielded a uniform “wound” to the monolayer. (A) Treatment with TIMP-1-GPI but not the control proteins, showed a dose dependent increase in wound closure. (B) The closing areas were calculated using imaging software NIS-Elements. (Video S1, S2, S3, S4, S5).
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