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Systemic risk factors for atherosclerosis are elevated in P. gingivalis infection.

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posted on 16.05.2014, 02:52 by Irina M. Velsko, Sasanka S. Chukkapalli, Mercedes F. Rivera, Ju-Youn Lee, Hao Chen, Donghang Zheng, Indraneel Bhattacharyya, Pandu R. Gangula, Alexandra R. Lucas, Lakshmyya Kesavalu

(A, B), Graphical representation of Table 3 (n = 6). CM – chylomicron, VLDL – very low-density lipoprotein, LDL – low-density lipoprotein, HDL – high-density lipoprotein, Pg – P. gingivalis, Con – control. C, Level of oxidized LDL in serum of 24 week-infected mice is significantly higher than in controls (**P<0.01; n = 6). (D) Infected mice had statistically significantly elevated levels of SAA relative to controls. *P<0.05. E, Infection with P. gingivalis significantly reduced serum nitric oxide relative to uninfected control mice (*P<0.05; n = 6).