Survival rate and fungal burden in H. capsulatum-infected C57BL/6 and 129/Sv mice.

C57BL/6 and sv129 mice were infected i.t. with 1×10⁶ (A) or 5×10⁵ (B) yeast cells, and their survival was followed for 60 days (n = 6). The fungal loads in the lungs (C) and spleen (D) of mice infected with 5×10⁵ yeast cells were evaluated at 7 and 14 days post-H. capsulatum infection. The data are expressed as the mean ± SEM from one representative experiment of a total of three experiments (n = 6/each experiment). *sv129 compared with C57BL/6. p<0.05 was considered significant.