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Survival rate and fungal burden in H. capsulatum-infected C57BL/6 and 129/Sv mice.

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posted on 2014-01-21, 03:52 authored by Adriana Secatto, Elyara Maria Soares, Gisele Aparecida Locachevic, Patricia Aparecida Assis, Francisco Wanderlei Garcia Paula-Silva, Carlos Henrique Serezani, Alexandra Ivo de Medeiros, Lúcia Helena Faccioli

C57BL/6 and sv129 mice were infected i.t. with 1×106 (A) or 5×105 (B) yeast cells, and their survival was followed for 60 days (n = 6). The fungal loads in the lungs (C) and spleen (D) of mice infected with 5×105 yeast cells were evaluated at 7 and 14 days post-H. capsulatum infection. The data are expressed as the mean ± SEM from one representative experiment of a total of three experiments (n = 6/each experiment). *sv129 compared with C57BL/6. p<0.05 was considered significant.