Study Design.

Serum was collected at the initial and final exercise sessions of a 6-week training intervention. Time points of serum collection were 1 hour prior to exercise (Rest) and 2, 5, 15, 35 and 75 minutes after exercise termination. Serum concentrations of angiogenic markers (MMP-2, MMP-9, VEGF and endostatin) were determined for all serum samples, BrdU incorporation assay was performed with the serum samples indicated with (*): Rest, +2 min and +75 min.