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Steady-state activation of Gq under cellular conditions.

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posted on 2008-08-15, 01:13 authored by Marc Turcotte, Wei Tang, Elliott M. Ross

Fractional activation Z was simulated at varying total concentrations of receptor and GAP, with 1.6×10−4 M Gq, for cytosolic concentrations of 200 µM GTP, 20 µM GDP, and 1 mM Pi. Z values for colors on the contour plot are defined in the reference bar below. Protein concentrations are expressed with reference to the membrane volume.