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Sleepiness promotes widespread increases in functional connectivity.

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posted on 05.11.2015 by Diederick Stoffers, B. Alexander Diaz, Gang Chen, Anouk den Braber, Dennis van ‘t Ent, Dorret I. Boomsma, Huibert D. Mansvelder, Eco de Geus, Eus J. W. Van Someren, Klaus Linkenkaer-Hansen

A total of eleven combinations of ICNs and ARSQ dimensions showed significant associations between functional connectivity and ARSQ score at a cluster-wise Bonferroni-corrected significance threshold of PFWE = .00025. Orthogonal slices through the peak voxel are shown on the left of each panel; ICNs are defined by the ICA spatial maps thresholded at Z = 2.3 and displayed in green, clusters of voxels showing significant associations (2.62 < t < 6) in a gradient from red to yellow, overlaid on a standard brain template in radiological convention (left = right). Number of significant voxels, maximum t-statistic and peak voxel coordinates are displayed at the top right, scatter plots showing the mean functional connectivity value in significant clusters (y-axis) plotted against the relevant ARSQ measure are shown in the bottom right of each panel.