Serum IP-10 concentrations at day 0 and 7 of therapy.

Each set of 2 connected points represent data from a single patient from Nigeria (blue) or Nepal (red). Panel A: IP-10 concentrations of HIV-positive, Smear (Sm) positive, and culture/Xpert (Cult) positive patients. The MDR-TB patient is shown with a dashed line. One smear-positive patient had missing culture (Open symbols). Panel B-D: IP-10 concentrations of HIV- Sm+ (B), HIV+ Sm- (C), and HIV- Sm- (D) culture/GeneXpert positive patients. E: Concentrations from Sm-Cult- patients, of which 4 had missing HIV result (open square symbols) and all others were HIV- (round symbols). IP-10 levels in culture/GeneXpert positives were significantly different between day 0 and day 7 (p<0.0001). For culture/GeneXpert negatives p>0.05 between day 0 and day 7.