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Sequence alignment of the amino acid sequences of the ovine, caprine, human and monkey Prt (prion protein testis-specific).

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posted on 20.02.2013, 00:18 by Jorge Pimenta, Ana Domingos, Pedro Santos, Carla C. Marques, Cátia Cantante, Ana Santos, João P. Barbas, Maria C. Baptista, António E. M. Horta, Aldino Viegas, Patrícia Mesquita, João Gonçalves, Carlos A. Fontes, José A. M. Prates, Rosa M. L. N. Pereira

Top lane: complete ovine Prt sequence GenBank: ABO86196.1. Second lane: complete caprine Prt sequence, GenBank: CAL85353.1. Third lane: truncated (42–94 a.a.) human Prt sequence, UniProtKB/Swiss-Prot: Q86SH4.1. Forth lane: truncated (42–94 a.a.) Rhesus monkey (Macaca mulatta) Prt sequence, NCBI Reference Sequence: XP_001112273.2. Blue letters with arrows on top: different amino acids between sheep and goat Prt; Asterisk (*) denotes identical residue; colon (:), conservative change; period (.), related substitution. Dark red indicates residues aligned in a similar fashion among all the individual MSAs; Dark yellow, orange and red residues can be considered to be reliably aligned. Alignment using the M-Coffee program [28].


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