Sequence alignment of selected tetraspanins.
figureposted on 2015-07-28, 04:06 authored by Karin Skaar, Henryk J. Korza, Michael Tarry, Petra Sekyrova, Martin Högbom
Predicted localization of transmembrane helices with TOPCONS server  are indicated with a gray background. Residues conserved across the family–indicated in yellow and predicted glycosylation sites  are indicated with a red background. Sequence alignments were generated with the ClustalW server  by feeding 219 tetraspanin sequences from diverge spices to improve alignment statistics.
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Saccharomyces cerevisiae Tetraspaninsmultimolecular complexesyeast cellseukaryotic speciespolymer techniqueSubcellular localizationreport expression screeningcancer developmentMammalian genomes encodefusion proteinsIntegral membrane proteinstetraspanin superfamily15 membersmembrane fractiontetraspanin homologssubcellular distributionprotein fusion proteinsprotein samplescell migrationendoplasmic reticulum membranes