Segmentation results using the HC-EM-MoMG method for a patient with moyamoya disease.
(a) Consecutive trans-axial DSC-MRI (15th to 38th second). (b) Right cerebral angiography at early arterial phase on lateral projection shows stenosis of the distal internal carotid artery, proximal segments of the anterior and middle cerebral arteries (red arrows). The moyamoya vessels are seen in the basal ganglia region (blue yellow). The prominent branches of external carotid artery (arrowheads) form the extracranial collaterals. (c) Another arterial phase angiogram taken at 1.5 seconds after (a) shows the late arrival blood supply (arrows). Her right parietal region is less blood-irrigated (arrowheads). (d) A trans-axial T2-weighted MR image shows abnormal high signals in her parietal-occipital region (arrows). (e) Diffusion-weighted image confirms an acute infarct with diffusion restriction (arrows). (f) Segmented results shows eight hemodynamic components, namely artery (red), gray matter (green), white matter (brown), CSF (gray), ischemic or infarct area (purple), areas supplied by collateral arteries with risk of infarct (cyan), vein and sinus (blue), and artifacts (dark blue). (g) The averaged signal-time curves of corresponding tissues demonstrated that the artery arrived earliest with maximum T2* signal drop followed by the GM or vein+sinus, WM or CSF, risk of infarct, and infarct. (h) rCBV map (scale unit is ml⋅100 g−1). (i) rCBF map (scale unit is ml⋅100 g−1⋅min−1). (j) MTT map (scale unit is second).