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Schematic representation of budding and lytic virus replication strategies.

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posted on 17.11.2011, 00:22 by Andrew J. Yates, Minus Van Baalen, Rustom Antia

On the left, budding viruses: a time after infection of the cell, sufficient epitopes are presented on the cell surface for CTL to recognise and kill the cell; virion production causes an increase in cell mortality, , at a later time ; and at a later time , virions begin to be shed from the cell at constant rate . On the right, lytic viruses: beginning a time after infection the cell becomes visible to CTL, after time , stress induced by virus replication within the cell generates an additional mortality rate ; and the infected cell bursts and releases virions a time after infection. In both figures, is the duration of a cell's visibility to CTL before virus release begins. Intervals between events are not shown to any scale.

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