Schematic representation of budding and lytic virus replication strategies.
On the left, budding viruses: a time after infection of the cell, sufficient epitopes are presented on the cell surface for CTL to recognise and kill the cell; virion production causes an increase in cell mortality, , at a later time ; and at a later time , virions begin to be shed from the cell at constant rate . On the right, lytic viruses: beginning a time after infection the cell becomes visible to CTL, after time , stress induced by virus replication within the cell generates an additional mortality rate ; and the infected cell bursts and releases virions a time after infection. In both figures, is the duration of a cell's visibility to CTL before virus release begins. Intervals between events are not shown to any scale.