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Schematic representation of a micelle and interactions with monomers.

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posted on 07.08.2014, 03:15 by Erwan Hingant, Pascaline Fontes, Maria Teresa Alvarez-Martinez, Jacques-Damien Arnaud, Jean-Pierre Liautard, Laurent Pujo-Menjouet

The blue pentagons represent the PrPC monomers, the big orange spherical structure stands for a micelle consisting of monomers, and the orange spheres (out of micelle) are the PrP* monomers stabilized by micelles. Both types of monomers, PrPC and PrP*, interact with the micelles by association-dissociation with rates given by , , and depending on the number of monomers that form the micelle.