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Scent marking behavior in the absence and presence of female urine in adult male Shank1 mice.

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posted on 2013-02-20, 17:47 authored by Markus Wöhr, Florence I. Roullet, Albert Y. Hung, Morgan Sheng, Jacqueline N. Crawley

(A) Number of scent marks deposited near (within 10 cm2 around) the female urine spot deposited by male subjects before they had an experience of social interactions with a female, and 7 days after they had a 5 minute experience of social interactions with a female. (B) Time spent in proximity to the female urine spot (10 cm2) by male subjects before they had an experience of social interactions with a female and after female experience. (C) Total number of scent marks deposited throughout the entire open field during the 5 min test session in the open field containing urine from a female C57BL/6J mouse deposited by male subjects before they had an experience of social interactions with a female and after female experience. (D) Total number of scent marks deposited throughout the entire open field during the 60 min habituation session in the clean open field without female urine deposited by male subjects before they had an experience of social interactions with a female and after female experience. Black bar: Shank1+/+ wildtype littermate control mice; striped bar: Shank1+/ heterozygote mice; white bar: Shank1/ null mutant mice. Data are presented as means ± standard errors of the mean. * p<0.050 vs. Shank1+/+; # p<0.050 vs. Shank1+/.

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