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SR Ca2+ load in CASMCs of diabetic mouse. A

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posted on 03.01.2013 by Angélica Rueda, María Fernández-Velasco, Jean-Pierre Benitah, Ana María Gómez

. Representative caffeine-induced Ca2+ transients in Fura-2 loaded CASMCs from control (upper graph) and db/db mice (bottom graph); bottom traces indicate the start and end of caffeine applications (10 mmol/L). Breaks in x-axis indicate a 5-min interval between the first and the second caffeine application to allow the recovery of SR Ca2+ stores. B. Bar graph of averaged caffeine-induced Ca2+ transients. *P<0.05 C. Bar graph of averaged basal [Ca2+]i concentrations in CASMCs from control (open bar, n = 50 cells) and db/db mice (fill bar, n = 62 cells).

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