Risk and relative risk for heterozygotes to develop FMF.
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posted on 2013-07-03, 03:06 authored by Isabelle Jéru, Véronique Hentgen, Emmanuelle Cochet, Philippe Duquesnoy, Gaëlle Le Borgne, Emmanuel Grimprel, Katia Stankovic Stojanovic, Sonia Karabina, Gilles Grateau, Serge AmselemConsidering the prevalence of FMF reported in Turks and Sephardic Jews [25]–[26], as well as the distribution of MEFV genotypes in affected and healthy individuals, we could make a rough estimate of the risk and relative risk for heterozygotes to develop FMF, as compared to healthy individuals. Risks are indicated by labels next to each sector, relative risks are displayed below each genotype distribution. m: mutated MEFV allele; N: normal MEFV allele.
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geneticsHereditygenotypesHuman geneticsAutosomal recessiveGenetics of diseaseMolecular geneticspopulation geneticsimmunologyimmunityinflammationInnate immunitystatisticsBiostatisticsClinical geneticsClinical immunologyClinical research designStatistical methodsGastroenterology and hepatologyNon-clinical medicineHealth care policyHealth risk analysisHealth statisticsrheumatologyheterozygotes
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