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Relative survival after 22 hours of exposure to antibiotics.

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posted on 03.01.2013, 00:55 by Paul J. T. Johnson, Bruce R. Levin

Means and standard deviations of the fraction of persisters following treatment for 10 independent cultures, and 10 cultures derived from mixtures of equal amounts of the 10 independent cultures, with either 5× MIC or 20× MIC of four antibiotics. (A) Ciprofloxacin, (B) Gentamicin, (C) Oxacillin, and (D) Vancomycin. In these experiments, the initial density of cells exposed to the antibiotics was on the order of 106 to reduce the incidence of mutants for ciprofloxacin (none were observed).


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