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Relative binding of C. jejuni 11168 to Neu5Ac containing structures in the presence of sialyltransferase and sialidase inhibitors.

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posted on 21.02.2013, 06:32 by Christopher J. Day, Joe Tiralongo, Regan D. Hartnell, Carie-Anne Logue, Jennifer C. Wilson, Mark von Itzstein, Victoria Korolik

Relative fluorescent levels of treated 11168-GS 42°C (A) and C. jejuni 11168-O 25°C (B) compared to normal C. jejuni binding to Neu5Ac containing glycans. (Neu5Ac2en, black bar; 4-guanidino-Neu5Ac2en, grey bar; and CMP, white bar). For the structure of the individual glycans refer to Table 2.