Relationship of C. symbiosum Ammonia Monooxygenase (amo) Gene Cluster to Other Uncultivated Crenarchaeal Sequences

(A) Comparison of the genomic interval containing ammonia monooxygenase genes in C. symbiosum with two related environmental fosmid sequences, one obtained from mesopelagic seawater (AF393466) and the other from terrestrial soil (AJ627422).

(B) Comparison of the order and composition of the C. symbiosum ammonia monooxygenase (acc) gene cluster and unlinked amoC3 locus in relation to the bacterial operon from N. europaea, several highly related contig intervals identified in the environmental database of SAR WGS sequences, and a terrestrial soil sequence. Protein identity (top) and similarity (bottom) percentages between predicted gene products identified in C. symbiosum are shown within the corresponding shaded boxes. See Tables S1– S3 for more information.