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Reduced T cell infiltrate in K14E7 mice containing mutant Rb.

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posted on 2013-02-27, 09:28 authored by Allison Choyce, Michelle Yong, Sharmal Narayan, Stephen R. Mattarollo, Amy Liem, Paul F. Lambert, Ian H. Frazer, Graham R. Leggatt

Representative FACs plots are shown for ear skin from K14E7, K14E7xRb mutant, C57BL/6 and Rb mutant mice stained with CD45 and CD3 (top panels). The data for the K14E7xRb mutant was representative of 4/5 mice tested with the outlying mouse having an unusually high T cell fraction in the skin of 20%. The lower panels are representative haematoxylin and eosin staining of ear skin from each of the corresponding mice listed in the top panels.