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Recovery of Candida albicans from infected Galleria mellonella larvae.

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posted on 15.11.2013, 03:05 authored by Nadja Rodrigues de Melo, Ahmed Abdrahman, Carolyn Greig, Krishnendu Mukherjee, Catherine Thornton, Norman A. Ratcliffe, Andreas Vilcinskas, Tariq M. Butt

The number of C. albicans CFUs recovered from G. mellonella larval fat body and hemolymph 24 h post-drug treatment and infection. CFUs recovered from the fat body of the CA group were significantly higher than all the other groups (*p<0.01, n = 10). In contrast, CFUs recovered from the hemolymph of MYR+CA group were significantly higher (**p<0.001, n = 10) than all the other groups. In addition, only in the MYR+CA group were the CFUs recovered from hemolymph significantly higher than from the fat body (**p<0.001, n = 10). The drug treatments and abbreviations are as in Figure 1. Error bars indicate standard errors. Each experiment was triplicated.


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