Recovery accuracy for TFs based on simulated trials.
figureposted on 2015-11-12, 03:05 authored by Gaurang Mahajan, Shekhar C. Mande
Comparison of recovery accuracy values yielded by the default method and iterative search over 104 random trials in the noiseless limit (left) and with 5% misclassification rate added to the binarized differential expression profile (right). The trials have been sorted in decreasing order of the difference between the accuracy values (Method C—default).
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gene expressiongenome-scale expression alterationComparative analysistranscription factor enrichmentapproachliterature curationCombinatorial Approach High-throughput experimentsGene ExpressionPerturbed Regulatory Factorsfactor enrichmentaggregated targettranscriptional regulatorsmotif scanningcoli microarraynetwork dataiterative search methodmethodologytranscriptomic changesscale informationtarget setsexpression profilesfactor overexpression data