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Rapamycin and Torin1 effects on neurite outgrowth in presence of HMB.

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posted on 2015-08-12, 03:38 authored by Rafael Salto, Jose D. Vílchez, María D. Girón, Elena Cabrera, Nefertiti Campos, Manuel Manzano, Ricardo Rueda, Jose M. López-Pedrosa

Cells were pre-treated with rapamycin 20nM or Torin1 10 nM and then treated with 25 μM HMB for 48 h. The inhibitor was maintained during the experiment. Results represent means ± SEM (n = 8). * p<0.05 versus control cells. # p<0.05 versus HMB treated cells.