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RNA editing in Xenopus tropicalis.

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posted on 2010-05-20, 02:35 authored by Alexander Wait Zaranek, Erez Y. Levanon, Tomer Zecharia, Tom Clegg, George M. Church

(A) Evidence for RNA editing can be seen in this locus as multiple traces of RNA origin align to it with numerous A-to-G mismatches. The trace accession numbers and their coordinates are given in the multiple alignment. (B) Predicted RNA structure of the genomic locus indicates a long and stable dsRNA structure which is a favorite target for editing by ADARs. Each editing site from the multiple alignment is marked by an arrow. The length of the arrow corresponds to the editing level.

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