Figure_2.tif (281.04 kB)

RNA editing efficiency is highly regulated between different areas of the nervous system.

Download (0 kB)
figure
posted on 23.11.2010 by Claudia Colina, Juan Pablo Palavicini, Deepa Srikumar, Miguel Holmgren, Joshua J. C. Rosenthal

(A) An example of the fluorescent poison-primer extension assay [26] used to measure the frequency of the I877V edit in the giant fiber lobe (GFL; giant axon system) and the optic lobe (OL) neurons. (B) Cumulative results from a broad range of tissues (all numbers are expressed as mean ± s.d. N = 4 for each tissue). To determine the editing efficiency of all four editing sites in different tissues, the full-length SqNaKα1 cDNA was amplified using cDNA specific to different regions of the Loligo nervous system [42],[43] and then used as a template for the assay.

History

Licence

Exports

Logo branding

Licence

Exports