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Qualitative comparison of unmodified and capsid mutated AAV vectors in vivo.

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posted on 26.04.2013, 00:39 by Christine N. Kay, Renee C. Ryals, George V. Aslanidi, Seok Hong Min, Qing Ruan, Jingfen Sun, Frank M. Dyka, Daniel Kasuga, Andrea E. Ayala, Kim Van Vliet, Mavis Agbandje-McKenna, William W. Hauswirth, Sanford L. Boye, Shannon E. Boye

Fundoscopy (red channel only) of Rho-GFP mice 4 weeks post-injection with unmodified and capsid-mutated scAAV-smCBA-mCherry vectors (1.5×109 vg delivered). Exposure and gain settings were the same across all images.