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Q-Q and Manhattan Plots for the hyperopia analysis excluding the ERF cohort a) Q-Q plot for association between all SNPs analyzed and hyperopia in the meta-analysis excluding the ERF cohort.

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posted on 2014-09-18, 03:47 authored by Claire L. Simpson, Robert Wojciechowski, Konrad Oexle, Federico Murgia, Laura Portas, Xiaohui Li, Virginie J. M. Verhoeven, Veronique Vitart, Maria Schache, S. Mohsen Hosseini, Pirro G. Hysi, Leslie J. Raffel, Mary Frances Cotch, Emily Chew, Barbara E. K. Klein, Ronald Klein, Tien Yin Wong, Cornelia M. van Duijn, Paul Mitchell, Seang Mei Saw, Maurizio Fossarello, Jie Jin Wang, Ozren Polašek, Harry Campbell, Igor Rudan, Ben A. Oostra, André G. Uitterlinden, Albert Hofman, Fernando Rivadeneira, Najaf Amin, Lennart C. Karssen, Johannes R. Vingerling, Angela Döring, Thomas Bettecken, Goran Bencic, Christian Gieger, H.-Erich Wichmann, James F. Wilson, Cristina Venturini, Brian Fleck, Phillippa M. Cumberland, Jugnoo S. Rahi, Chris J. Hammond, Caroline Hayward, Alan F. Wright, Andrew D. Paterson, Paul N. Baird, Caroline C. W. Klaver, Jerome I. Rotter, Mario Pirastu, Thomas Meitinger, Joan E. Bailey-Wilson, Dwight Stambolian

Each dot represents an observed statistic (defined as -log10 P) versus the corresponding expected statistic. The red line corresponds to the null distribution. b) Manhattan plot for association between all SNPs analyzed and hyperopia in the meta-analysis excluding the ERF cohort. Each dot represents an observed statistic (defined as -log10 P). The darker gray line corresponds to the genome-wide significance threshold and the lighter gray line represents the suggestive threshold.

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