Positive Linear Regression of Auditory Cortical Deactivation with Cognitive Performance (MMSE) in All Participants

Left: results are superimposed on a standard MRI template. Yellow indicates a significant relationship of cerebral deactivation with the MMSE: (A) axial slice, cranial aspect; (B) coronal slice, dorsal aspect (results are displayed at p < 0.005, for illustration purposes).

Right: Regression analysis (red indicates regression line) of the fitted and adjusted rCBF response (blue points, arbitrary units) to active navigation in relation to the MMSE score at the position of the significant cluster (Talairach coordinates x, −56; y, −14; z, −2; p < 0.001, uncorrected).