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Percentage of good and moderate EULAR response rate (%) in RA patients after 6 months of RTX therapy.

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posted on 30.07.2012, 02:41 by Gianfranco Ferraccioli, Barbara Tolusso, Francesca Bobbio-Pallavicini, Elisa Gremese, Viviana Ravagnani, Maurizio Benucci, Edoardo Podestà, Fabiola Atzeni, Alice Mannocci, Domenico Biasi, Mariangela Manfredi, Piercarlo Sarzi-Puttini, Bruno Laganà, Carlomaurizio Montecucco

Patients were grouped according to the number of fulfilled parameters (corticosteroids therapy, number of circulating lymphocytes <1875/μl, plasma BAFF levels <1011 pg/ml and RF-IgM >52.1 U/ml). Good response was reached in 20.8% of RA patients that fulfilled 0–1 parameter, in 29.2% of subjects that fulfilled 2–3 parameters and in 54.5% of subjects that fulfilled 4 parameters (Fisher's exact test between 4 parameters and 0–3 = 0.08). Moderate-response was reached in 41.7% of RA patients that fulfilled 0–1 parameter, in 54.5% of subjects that fulfilled 2–3 parameters and in 72.7% of subjects that fulfilled 4 parameters (χ2 test = 3.02, df = 2; p = 0.22). *p = 0.046: percentage of good response in patients fulfilling 4 vs 0–1 parameters.

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