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Patterned stimulation (10 bursts at 1.25 Hz with each burst consisting of 10 stimuli at 25 Hz) induces long term potentiation of IPSCs in neocortical slices from PND12-15 animals.

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posted on 20.02.2013, 20:29 by Seena S. Mathew, John J. Hablitz

A: specimen records showing representative traces before and after stimulation under control conditions (left) and in the presence of APV (right). Response enhancement was not observed in the presence of APV. B: summary plot showing time course plots of IPSC amplitude before and after patterned stimulation. LTP was seen in control and BAPTA groups but not in the presence of APV.