Figure_2.tif (2.48 MB)
Pathway site-moiety map of SDH (yellow) and SK (purple).
figure
posted on 2013-07-04, 02:13 authored by Kai-Cheng Hsu, Wen-Chi Cheng, Yen-Fu Chen, Wen-Ching Wang, Jinn-Moon Yang(A) Superimposed binding sites of SDH and SK by the anchor-based alignment method. Four pathway anchors were identified despite low sequence and structure similarities of SDH and SK. Hydrogen-bonding and van der Waals anchors are colored in green and gray, respectively. (B) Common moiety preferences of four pathway anchors.
