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Partial Nav-CLS in a population and apparently first order activation kinetics.

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posted on 19.02.2013, 23:26 by Na Yu, Catherine E. Morris, Béla Joós, André Longtin

Equilibrium activation values (m3, and m ) of co-existing intact Nav and CLS Nav channels plotted as a function of Vm. Black solid and black dashed line represent m3 for intact and 20 mV CLS channels with f = 1. For a membrane with large Nav-CLS injury given by: LSi = [0,20]mV and fi = [0.3,0.7], the gray bold line denotes . Red line: m of the intact channels.

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