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Parasitemia levels after 7 days of oral administration of fexinidazole.

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posted on 19.02.2013, 20:53 by Maria Terezinha Bahia, Isabel Mayer de Andrade, Tassiane Assíria Fontes Martins, Álvaro Fernando da Silva do Nascimento, Lívia de Figueiredo Diniz, Ivo Santana Caldas, André Talvani, Bernadette Bourdin Trunz, Els Torreele, Isabela Ribeiro

Parasitemia curve obtained from 6 mice infected with 5000 trypomastigotes of T. cruzi Y strain and treated daily with doses of fexinidazole 100, 200, and 300 mg/kg of body weight (mpk) or benznidazole 100 mpk for 7 consecutive days. Arrows indicate the first and the last day of treatment. IC: infected and untreated control.

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