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PTM cross-talk between K4me3 and K9me3 on cc-KDM4C.

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posted on 2013-07-02, 03:14 authored by Brian Lohse, Charlotte Helgstrand, Jan B. L. Kristensen, Ulrike Leurs, Paul A. C. Cloos, Jesper L. Kristensen, Rasmus P. Clausen

Enzyme kinetics for trimethylated substrate H3(1–24)K9me3 (2) and bis-tri-methylated substrate H3(1–24)K4me3-K9me3 (3).

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Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro
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Keywords

BiochemistryenzymesEnzyme kineticsproteinsProtein chemistryProtein interactionsgeneticsepigeneticsHistone modificationgene expressionMolecular cell biologyoncologycross-talkk4me3k9me3

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