PRR over-expression activates ERK1/2 and Akt phosphorylation in Neuro-2A cells.
A representative western blot and semi- quantitative graph for ERK1/2 (A) and Akt (B) phosphorylation in the presence of wortmannin (2 µM) or U0126 (10 µM) 3 d post AAV-hPRR-eGFP or control virus infection in Neuro-2A cells. All the experiments were done in the presence of losartan (10 µM). *P<0.05 vs. AAV-eGFP in the same treatment. # P<0.05 vs. vehicle treatment.