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P0 outward currents are insensitive to TEA.

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posted on 2013-02-19, 18:18 authored by José A. Ramírez-Latorre

Perforated whole-cell current of a SN DA neuron at P0. The whole cell patch was obtained and the current was recorded for five minutes to assay for decay. After 5 min, 20 mM TEA was applied in a fast perfusion system. No appreciable diminution of the current was observed. The slice was then washed. After the wash, 1 M IbTx was applied. No effect was observed on the outward current. The voltage protocol is indicated below the trace.

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