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Number of vesicle release sites and probability of vesicle release are reduced for MuSK-MG-affected TS preparations.

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posted on 01.12.2014, 03:13 by Vishwendra Patel, Anne Oh, Antanina Voit, Lester G. Sultatos, Gopal J. Babu, Brenda A. Wilson, Mengfei Ho, Joseph J. McArdle

Equations 1 and 2 were used to calculate the number of vesicle release sites (A) and the probability of neurotransmitter release (B), respectively. Bars are shown as the mean + SEM for control (34 NMJs, 12 mice) and MuSK-MG-affected (31 NMJs, 8 mice) preparations; * and *** denote P<0.05 and P<0.0001, respectively.