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Nucleotide substitutions during serial passages of the S3 series stocks.

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posted on 19.02.2013 by Asuka Yoshida, Takemasa Sakaguchi, Takashi Irie

(A) The regions of C ORF containing stop codons introduced in the 4C(-) virus are shown. (B) The electrographs of the region shown in (A) of the S3 series stocks. Appreciable A-to-G (U-to-C) transition substitutions are indicated as arrows, and among these, those causing reversions of introduced stop codons are indicated as stars.

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