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NiV in ferret tissues.

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posted on 21.02.2013, 04:01 authored by Katharine N. Bossart, Zhongyu Zhu, Deborah Middleton, Jessica Klippel, Gary Crameri, John Bingham, Jennifer A. McEachern, Diane Green, Timothy J. Hancock, Yee-Peng Chan, Andrew C. Hickey, Dimiter S. Dimitrov, Lin-Fa Wang, Christopher C. Broder

Immunohistochemistry was done using a rabbit antiserum against Nipah virus nucleoprotein with haematoxylin counterstain as previously described [22]. (A) ferret 7–50000, lung tissue with severe acute necrotizing alveolitis and vasculitis. Antigen present in syncytia (long arrow) and blood vessel wall (short arrow). (B) ferret 4–500, antigen staining in arachnoid membrane of the meninges, with non-suppurative inflammation. (C) ferret 7–50000, kidney with antigen staining in necrotic glomerular tuft and tubular epithelium; syncytia present in the epithelium of Bowman's capsule (arrow). (D) ferret 4–500, inflammation of the peri-tracheal tissues. Antigen present in blood vessel walls, syncytial cell (arrow). Scale bars = 50 µm.

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