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Network for GBM subtype-specific drug candidates.

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posted on 01.08.2014, 03:00 by Young Taek Oh, Hee Jin Cho, Jinkuk Kim, Ji-Hyun Lee, Kyoohyoung Rho, Yun-Jee Seo, Yeon-Sook Choi, Hye Jin Jung, Hyeon Suk Song, Doo-Sik Kong, Ho Jun Seol, Jung-Il Lee, Yeup Yoon, Sunghoon Kim, Do-Hyun Nam, Kyeung Min Joo

Eight drug candidates were directly/indirectly liked to a number of subtype-specific genes; Clomipramine: 57 proneural-specific genes; Gefitinib: 64 proneural-specific genes; Beta-Nicotinamide Adenine Dinucleotide Hydrate: 35 neural-specific genes; Bicuculline: 5 neural-specific genes; Pravastatin: 100 mesenchymal-specific genes; Resveratrol: 86 mesenchymal-specific genes; Irinotecan: 20 classical-specific genes; Paclitaxel: 79 classical-specific genes.