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Network construction of co-expressed genes in relation to psychosis and autism spectrum disorders in 22q11DS.

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posted on 22.07.2015, 03:02 authored by Maria Jalbrzikowski, Maria T. Lazaro, Fuying Gao, Alden Huang, Carolyn Chow, Daniel H. Geschwind, Giovanni Coppola, Carrie E. Bearden

A) Dendogram of modules identified through Weighted Gene Co-expression Analysis, created through linkage hierarchical clustering of genes. B) Module-Trait relationships for age, gender, psychotic disorder diagnosis, autism spectrum disorder diagnosis, and positive symptoms, as measured by the SIPs. Numbers shown represent Pearson correlations between the modules and traits. P-values are in parentheses. Numbers on the color bar refer to the strength of the correlation in the table (red = 1, green = -1).