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Nanosecond pulsed electric field generator.

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posted on 28.08.2012, 01:46 by Dong Yin, Wangrong G. Yang, Jack Weissberg, Catherine B. Goff, Weikai Chen, Yoshio Kuwayama, Amanda Leiter, Hongtao Xing, Antonie Meixel, Daria Gaut, Fikret Kirkbir, David Sawcer, P. Thomas Vernier, Jonathan W. Said, Martin A. Gundersen, H. Phillip Koeffler

Image showing the experimental nanosecond pulsed electric field generator and hand piece for delivery of nsPEF exposure to skin tumors in vivo (Panel A). Enlarged image showing nsPEF delivery tip; the tip is placed into the tumor during exposure. Significant components of the tip include five short 30-gauge needle electrodes, the center electrode being the positive with four surrounding return electrodes, each spaced 1.75 mm from the center electrode (Panel B). Image showing typical pulse waveform, with 7KV amplitude and 14 ns pulse width (FWHM) delivered into a fixed 100 ohm load (Panel C).

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