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Multiple-sequence alignment of ABCA4 from different species.

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posted on 24.04.2014, 02:43 by Xiao Zhang, Xianglian Ge, Wei Shi, Ping Huang, Qingjie Min, Minghan Li, Xinping Yu, Yaming Wu, Guangyu Zhao, Yi Tong, Zi-Bing Jin, Jia Qu, Feng Gu

Multiple-sequence alignment in ABCA4 from different species revealed that these mutations were located within a highly conserved region. The mutations were highlighted by red box. Majority of the identified mutations (4 of 6) were located within the alpha-helix regions. α-helices are displayed as squiggles; β-strands as arrows; strict β-turns as TT letters.