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Mucus penetrability of nanoparticles in mouse distal colon explants.

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posted on 2014-06-12, 03:15 authored by Ana Sadio, Jenny K. Gustafsson, Bruno Pereira, Carla Pereira Gomes, Gunnar C. Hansson, Leonor David, Ana Paula Pêgo, Raquel Almeida

(A) Representative Z – stack projections of TMC/siRNA nanoparticles in distal colon explants and the corresponding normalised intensity plots; tissue is blue and nanoparticles are red. Scale bars 100 µm. (B) Percentage of the total fluorescence intensity of TMC and CHimi2/siRNA nanoparticles in each plan (tissue, lower half, and upper half) at each time point. Data are presented as means ± SD (n = 3).

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