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Mouse ChIP-seq results MotifSpec outperforms DREME when run on ChIP-seq data for 13 transcription factors from mouse embryonic stem cells.

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posted on 2015-10-14, 04:25 authored by Rahul Karnik, Michael A. Beer

The left panel shows a plot of the AUC for the top motif reported by MotifSpec against the AUC for the top motif reported by DREME, while the right panel shows the improvement in AUC for the MotifSpec motif relative to the DREME motif.

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expression clusters binding specificities search space discriminative motifs novel motifs sequencing technologies genomic binding pwm DNA Binding Motifs algorithm expression similarity accessibility data expression datasets Position weight matrix Discriminative Objective Function

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Mouse ChIP-seq results MotifSpec outperforms DREME when run on ChIP-seq data for 13 transcription factors from mouse embryonic stem cells.

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