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Monochromatic processes are enriched in specific high-level functional categories.

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posted on 24.02.2011, 01:37 authored by Magali Michaut, Anastasia Baryshnikova, Michael Costanzo, Chad L. Myers, Brenda J. Andrews, Charles Boone, Gary D. Bader

The count of processes in each category is normalized by the background distribution for all processes. For example, 35 processes among all 2,501 yeast processes are in the category ‘protein degradation/proteasome’ in the background distribution whereas 3 among the 50 monochromatic processes are in that category, resulting in an enrichment ratio of 3/50 * 2501/35 = 4.3.

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