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Modulation of Haemophilus-induced cytokine production in dendritic cells by Prevotella species.
figure
posted on 2013-02-20, 08:40 authored by Jeppe Madura Larsen, Daniel Bisgaard Steen-Jensen, Janne Marie Laursen, Jonas Nørskov Søndergaard, Hanieh Sadat Musavian, Tariq Mahmood Butt, Susanne BrixIL-23, IL-12p70 and IL-10 cytokine production measured in DC culture supernatants 24 h following stimulation with non-typeable Haemophilus influenzae (H. inf. NT) in combination with Prevotella melaninogenica (P. mel.), Prevotella nanceiensis (P. nan.) or Prevotella salivae (P. sal.). The effect of Prevotella species on Haemophilus-induced cytokine production was calculated relative to Haemophilus stimulation alone for each donor. The numbers identify individual donors (n = 3–5). *p<0.05, **p<0.01.
